ABSTRACT
Objective:To investigate the clinical efficacy of qualitative and staging diagnosis of rectal tumors with dual contrast-enhanced ultrasonography and interventional biopsy.Methods:A total of 300 patients with rectal tumors who received treatment in The First People's Hospital of Huzhou from December 2019 to March 2022 were included in this study. All patients underwent dual contrast-enhanced ultrasonography and interventional biopsy followed by focus resection. Taking the postoperative histopathological test results as the gold standard, the efficacy of dual contrast-enhanced ultrasonography and interventional biopsy in the localization, qualitative analysis, and staging of rectal tumors was analyzed.Results:The compliance rate of dual contrast-enhanced ultrasonography and interventional biopsy in the localization of rectal tumors was 100%. The sensitivity, specificity, and accuracy of the dual contrast-enhanced ultrasonography and interventional biopsy for qualitative diagnosis of rectal tumors were 94.8%, 97.8%, and 96.7%, respectively. The Kappa value used for assessing agreement in the qualitative diagnosis of rectal tumors between dual contrast-enhanced ultrasonography and interventional biopsy and postoperative tissue pathological examination results was 0.947. The area under the curve plotted for qualitative diagnosis of rectal tumors was 0.974. The sensitivity, specificity, and sensitivity of dual contrast-enhanced ultrasonography and interventional biopsy for diagnosis of stage I-III rectal cancer were 94.1%-97.8%. The Kappa values used for assessing agreement in staging diagnosis of stage I-III rectal cancer between dual contrast-enhanced ultrasonography and interventional biopsy and postoperative tissue pathological examination results were 0.923, 0.912, and 0.927, respectively. The areas under the curve plotted for staging diagnosis of rectal cancer were 0.961, 0.955, and 0.970, respectively.Conclusion:Dual contrast-enhanced ultrasonography and interventional biopsy have a high efficacy in the localization, qualitative diagnosis, and staging diagnosis of rectal tumors.
ABSTRACT
Objective:To observe the clinical effect and safety of lauryl alcohol injection under the guidance of ultrasound in the treatment of thyroid cyst.Methods:From February 2017 to February 2019, 148 patients with thyroid cyst who had been treated in the First People's Hospital of Huzhou were divided into study group and control group according to the random number table method, with 74 patients in each group.The patients in the study group were treated with ultrasound-guided percutaneous injection of lauryl alcohol, while the patients in the control group were treated with ultrasound-guided percutaneous injection of anhydrous ethanol.The changes of serum free triiodothyronine(FT 3), free tetraiodothyronine(FT 4) and thyroid-stimulating hormone(TSH) were compared before treatment and after treatment for 6 months.The curative effect was evaluated and the adverse reactions were observed after treatment. Results:There were no statistically significant differences in the serum TSH, FT 3 and FT 4 between the two groups before and after treatment( t=-0.514~0.624, P=0.513~0.852). The overall effective rate in the study group(94.59%) was significantly higher than that in the control group(82.43%)(χ 2=5.382, P=0.020). The overall incidence of adverse reactions in the study group(12.16%) was significantly lower than that in the control group(31.08%)(χ 2=7.815, P=0.005). Conclusion:Ultrasound-guided injection of lauryl alcohol and anhydrous ethanol did not affect the thyroid function of patients with thyroid cysts, while ultrasound-guided injection of lauryl alcohol is conducive to improve the efficacy of thyroid cysts, and the safety is higher, which is worthy of clinical application.